Zinc-Induced Copper Deficiency: Masquerade of Myelodysplastic Syndrome
نویسندگان
چکیده
منابع مشابه
Copper deficiency mimicking myelodysplastic syndrome
Copper is an essential element for all living organisms, because it has key activities in the metabolic enzymes such as cytochrome oxidase and superoxide dismutase, and in the proteins essential for iron homeostasis such as ceruloplasmin and hephaestin. In humans, the daily copper requirement is low, therefore copper deficiency is not so frequently a condition. However, we should be aware that ...
متن کاملCopper deficiency mimicking myelodysplastic syndrome
Copper deficiency is a rare cause of pancytopenia that may be mistaken for myelodysplastic syndrome. Cytoplasmic vacuolization in erythroid and myeloid precursors is found on bone marrow examination. Patients with a history of abdominal surgery who present with anemia and neutropenia with dysplastic changes should have copper levels checked.
متن کاملCopper deficiency masquerading as myelodysplastic syndrome.
We describe a woman with severe neutropenia and dependency on red blood cell transfusions who had previously undergone Billroth II surgery and whose bone marrow (BM) showed morphologic characteristics typical of myelodysplastic syndrome (MDS) with ringed sideroblasts. She had transient reversal of anemia and severe neutropenia after therapy with erythropoietin and granulocyte colony-stimulating...
متن کاملMicronutrient Deficiency Syndrome: Zinc, Copper and Selenium
Nutrients are defined as not only having nutritive values of participating in the metabolism and building the structures of cells but also being safe for human body. Nutrients are divided into two types, macronutrient and micronutrient, according to the proportion of the human body. Commonly, micronutrients include trace elements (trace mineral) and vitamins (complex organic molecules). It is d...
متن کاملCopper deficiency: an important consideration in the differential diagnosis of myelodysplastic syndrome.
Copper deficiency is an etiology of anemia, neutropenia, and bone marrow dysplasia that may be under-recognized. We report 5 patients with clinical presentation consistent with MDS who were found to be deficient in copper and whose hematologic abnormalities resolved with copper supplementation. We recommend copper level assessment in patients suspected of having low-risk MDS, especially those w...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2012
ISSN: 0002-9173,1943-7722
DOI: 10.1093/ajcp/138.suppl2.192